Thymic Development and Selection of T Lymphocytes
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Word Count
33,000 words, Guess
Page Count
132 pages
Identifiers
- ISBN-139783642402524
- ISBN-103642402526
- Better World Books9783642402524
- Open LibraryOL34501032M
Classifications
- LCCR-RZ
Description
The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.
Subjects
Other Editions
- Thymic Development and Selection of T Lymphocytes
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