Receptor Tyrosine Kinases
Structure, Functions and Role in Human Disease
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Word Count
110,000 words, Guess
Page Count
440 pages
Identifiers
- ISBN-139781493941193
- ISBN-101493941194
- Better World Books9781493941193
- Open LibraryOL34542474M
Classifications
- LCCQH301-705
Description
Receptor tyrosine kinases (RTKs) play critical roles in embryogenesis, normal physiology and several diseases, and over the last decade have become the number one targets of cancer drugs. Receptor Tyrosine Kinase: Structure, Functions and Role in Human Disease systematically covers, for the first time, the shared structural and functional features of the RTK family. Understanding the evolutionary origin of the 58 RTKs, their roles in invertebrates and in humans, as well as downstream signaling pathways, is essential for fundamental research and for attempts to develop pharmacological agents able to enhance or intercept their actions. The assembly of chapters written by experts underscores commonalities and is an ideal companion volume to The Receptor Tyrosine Kinase Family, which refers to specific subfamilies of RTKs, along with their unique landmarks.
Subjects
Topics
Other Editions
- Receptor Tyrosine Kinases
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