Pathophysiology for the Boards and Wards
Diagnosis and Therapy (Boards and Wards Series)
4 edition
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Author
Publication
2003-03-01 - Lippincott Williams & Wilkins
Language
English
Word Count
88,000 words, Guess
Page Count
352 pages
Physical Format
Paperback
Identifiers
- ISBN-101405103426
- ISBN-139781405103428
- Goodreads465326
- Open LibraryOL8404850M
First Sentence
1. Neurons undergo a variety of responses to cellular injury a. Manifestations of axonal damage 1) Distal Wallerian degeneration of axon & myelin 2) Proximal central chromatolysis cell body swelling, nucleus & Nissl body (rough endoplasmic reticulum) pushed to periphery 3) Prolonged axon injury retrograde cell body decay b. If synaptic input is lost, get transsynaptic degeneration c. Cell bodies injured directly by anoxia, glutamate excitotoxicity, apoptosis, metabolic storage diseases (Tay-Sachs, etc.)
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