Sumoylation
Molecular Biology and Biochemistry (Horizonbioscience)
1 edition
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Word Count
102,500 words, Guess
Page Count
410 pages
Physical Format
Hardcover
Identifiers
- ISBN-100954523288
- ISBN-139780954523282
- LibraryThing6058901
- Open LibraryOL8479651M
Description
This volume presents information on the history, evolution and mechanisms of sumoylation, discusses SUMO proteases, ligases and conjugation pathways, and reviews the impact on modification and nucleocytoplasmic transport, PML nuclear bodies, and transcriptional regulation. Specialist chapters cover the role of sumoylation in yeast, viruses and the tumor suppressor p53.
First Sentence
Until the early 1990s, ubiquitin was thought to be unique in terms of undergoing covalent linkage to other cellular proteins via its C-terminus, using a very specialized machinery.
Subjects
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